Loratadine Produces Antihistamine Activity without Adverse CNS, ECG or Cardiovascular Effects in Guinea Pigs
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چکیده
منابع مشابه
Lipid-lowering activity of Cow urine ark in guinea pigs fed with a high cholesterol diet
Objectives: Cow urine ark (CUA), known as “Amrita” as mentioned in Ayurveda, contains anti-hyperglycemic and antioxidant effects. Therefore, we designed the present study to evaluate the lipid lowering activity of CUA and its possible implication in metabolic syndrome. Materials and Methods: Thirty guinea pigs of either sex were divided into five groups: Group 1 and 2 serving as a vehicle a...
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Background: Several therapeutic effects including anti-asthma and dyspnea have been described for Plantago lanceolata. In the present study the antitussive effect of this plant was evaluated. Methods: The antitussive effects of aerosols of two different concentrations of Soxhlet and macerated ethanolic extracts, codeine and saline were tested by counting the number of coughs produced due to aer...
متن کاملAntitussive Effect of Rosa damascena in Guinea pigs
Several therapeutic effects including hypnotic, antispasmodic, treatment of abdominal and chest pain and strengthening the heart have been described for the flowers of Rosa damascena. North American Indian tribes use a decoction of the roots obtained from the Rosa damascena plant as a cough remedy and to treat eye problem. Therefore, in the present study the antitussive effect of this plant in ...
متن کاملCardiovascular and thermal responses to intravenous endotoxin in guinea pigs.
Changes in blood pressure, heart rate, and heat balance during febrile response to E. coli endotoxin were studied in unanesthetized guinea pigs at an ambient temperature of 24 degrees C. The heat balance was measured with direct and indirect calorimetry. An intravenous injection of endotoxin (5 micrograms X kg-1) produced characteristic biphasic changes in the intra-aortic temperature (Tar), he...
متن کاملAntitussive effect of Portulaca oleracea L. in guinea pigs
Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 1995
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000237062